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HelpTest ID NBLD0437 Purines and Pyrimidines Panel, Random, Urine
Secondary ID
41977Useful For
Evaluating patients with symptoms suspicious for disorders of purine and pyrimidine metabolism
Monitoring patients with disorders of purine and pyrimidine metabolism
Laboratory evaluation of primary and secondary hyperuricemias
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Purines and Pyrimidines Panel, USpecimen Type
UrineOrdering Guidance
This is recommended screening test for the initial workup of a suspected disorder of purine and pyrimidine metabolism, particularly when clinical features are nonspecific, and includes measurement of purines, pyrimidines, uric acid, and S-sulfocysteine. If the clinical features are suggestive of molybdenum cofactor deficiency, isolated sulfite oxidase deficiency, and hereditary xanthinuria, order SSCTU / S-Sulfocysteine Panel, Urine.
If this test is ordered with SSCTU, then SSCTU will be canceled.
Necessary Information
Patient's age is required.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 3 mL
Collection Instructions: Collect a random urine specimen.
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen | 90 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
|
Age range |
0-3 years |
4-6 years |
7-12 years |
13-18 years |
>18 years |
|
Uracil |
≤50 |
≤30 |
≤25 |
≤20 |
≤20 |
|
Thymine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Adenine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Hypoxanthine |
≤65 |
≤30 |
≤30 |
≤30 |
≤30 |
|
Xanthine |
≤54 |
≤21 |
≤35 |
≤15 |
≤20 |
|
Orotic |
≤4 |
≤4 |
≤3 |
≤3 |
≤5 |
|
Dihydroorotic acid |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Uric Acid |
350-2500 |
200-2000 |
200-1400 |
150-700 |
70-700 |
|
Deoxythymidine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Deoxyuridine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Thymidine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Uridine |
≤10 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Deoxyadenosine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Deoxyinosine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Deoxyguanosine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Adenosine |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Inosine |
≤6 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Guanosine |
≤4 |
≤3 |
≤3 |
≤3 |
≤3 |
|
5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside (AICAR) |
≤3 |
≤3 |
≤3 |
≤3 |
≤3 |
|
Succinyladenosine |
≤16 |
≤3 |
≤3 |
≤3 |
≤3 |
|
S-Sulfocysteine |
≤11 |
≤5 |
≤5 |
≤5 |
≤5 |
|
Dihydrouracil |
≤15 |
≤6 |
≤6 |
≤6 |
≤6 |
|
Dihydrothymine |
≤11 |
≤3 |
≤3 |
≤3 |
≤3 |
|
N-Carbamoyl-B-alanine |
≤30 |
≤10 |
≤10 |
≤10 |
≤10 |
|
N-Carbamoyl-B-aminoisobutyric |
≤20 |
≤3 |
≤3 |
≤3 |
≤3 |
All results reported as mmol/mol creatinine
Day(s) Performed
Tuesday, Thursday
Report Available
3 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542
Forms
If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.
SANFORD INTERFACE BUILD INFORMATION
| RESULT CODE | RESULT CODE DESCRIPTION |
|---|---|
| 21224 | INTERPRETATION (PUPYU) |
| 21225 | URACIL |
| 21226 | THYMINE |
| 21227 | ADENINE |
| 21228 | HYPOXANTHINE |
| 21229 | XANTHINE |
| 21230 | OROTIC ACID |
| 21231 | DIHYDROOROTIC |
| 21232 | URIC ACID |
| 21233 | DEOXYTHYMIDINE |
| 21234 | DEOXYURIDINE |
| 21235 | THYMIDINE |
| 21236 | URIDINE |
| 21237 | DEOXYADENOSINE |
| 21238 | DEOXYINOSINE |
| 21239 | DEOXYGUANOSINE |
| 21240 | ADENOSINE |
| 21241 | INOSINE |
| 21242 | GUANOSINE |
| 21243 | AICAR |
| 21244 | SUCCINLADENOSINE |
| 21245 | DIHYDROURACIL |
| 21246 | DIHYDROTHYMINE |
| 21247 | N-CARBOMOYL-BETA-ALANINE |
| 21248 | N-CARBAMOYL-BETA-AMINOISOBUTYRIC ACID |
| 21249 | REVIEWED BY |