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Test ID BLOD1199 Plasma Renin Activity, Pediatric

Specimen Type/Requirements

Lavender top (EDTA) -  Plasma

 

Collect EDTA blood (only) in a lavender-top venipuncture tube.

Mix gently by inversion.

Centrifuge immediately after collection.

Separate and freeze immediately.

 

It is critical that the plasma be transferred and frozen as quickly as possible to prevent cryoactivation of protein to renin (which results in falsely elevated renin levels).

 

This test requires its own frozen aliquot.

 

Note whether patient's posture was upright or supine at the time of collection.

 

Test is affected by hemolysis and lipemia. 

Specimen Volume

 

Preferred Volume   2.0 mL  
Minimum Volume   0.4 mL  

 

Performed Test Frequency

Monday through Friday

Report Available

2 - 5 days

Methodology

Liquid Chromatography/Mass spectrometry (LC/MS-MS)

Performing Lab

Esoterix

CPT

84244

Interface Build Information

Result Code  Result Code Description  
20231 Plasma Renin Act Peds

 

Stability/Transport

 

Room Temperature   not acceptable    
Refrigerated   not acceptable    
Frozen   14 days   preferred for transport  

 

Additional Information

Patient should consult their physician before being taken off medications at least three weeks prior to sample collection.

 

Dietary sodium levels during the period prior to testing can affect renin levels.

 

Sodium restriction tends to cause and increase in renin activity, while supplementation can result in lower levels.