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Test ID BLOD1115 Thyroglobulin, Tumor Marker, Serum

Useful For

Follow-up of patients with differentiated thyroid cancers after thyroidectomy and radioactive iodine ablation

Testing Algorithm

All specimens are screened for the presence of autoantibodies to thyroglobulin.

Reporting Name

Thyroglobulin, Tumor Marker

Specimen Type

Serum Red

Specimen Required

Patient Preparation: For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Collection Container/Tube: Red top

Submission Container/Tube: Plastic screw-top aliquot tube

Specimen Volume: 1 mL

Collection Instructions: Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 7 days
  Frozen  30 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross OK




Plasma, serum gel tube, whole blood

Reference Values


Athyrotic: <0.1 ng/mL

Intact thyroid ≤33 ng/mL


< 4.0 IU/mL

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Friday 6 a.m. - 12 a.m., Saturday 6 a.m. - 6 p.m.

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84432-Thyroglobulin, tumor marker

86800-Thyroglobulin antibody screen

Method Name

Immunoenzymatic Assay


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Oncology Test Request (T729)