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HelpTest ID BLOD0482 Intrinsic Factor Blocking Antibody, Serum
Reporting Name
Intrinsic Factor Blocking Ab, SUseful For
Confirming the diagnosis of pernicious anemia
Testing Algorithm
For more information, see Vitamin B12 Deficiency Evaluation.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
For a comprehensive workup of patients with suspected pernicious anemia, order ACASM / Pernicious Anemia Cascade, Serum, which initiates testing with measurement of vitamin B12. Depending of the vitamin B12 concentration, testing for intrinsic factor blocking antibody, gastrin, and methylmalonic acid may be added.
Specimen Required
Patient Preparation:
1. Patient should be fasting for 8 hours.
2. This test should not be performed on patients who have received a vitamin B12 injection or radiolabeled vitamin B12 injection within the previous 2 weeks.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Special Instructions
Reference Values
Negative
Day(s) Performed
Monday through Friday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86340
Report Available
1 day to 3 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Method Name
Immunoenzymatic Assay
Secondary ID
9335Sanford Interface Build Information
| Result Code | Result Code Description |
|---|---|
| 16277 | Intrinsic Factor Blocking Autoantibodies |
| 17473 | Comment |