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HelpTest ID BLOD0468 Clozapine, Serum
Secondary ID
42366Useful For
Monitoring patient compliance of clozapine treatment
An aid to achieving desired serum levels
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Clozapine, SSpecimen Type
Serum RedOrdering Guidance
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Â
1. Collect specimen immediately before next scheduled dose.
2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Additional Information: Therapeutic range (trough level) applies to specimens collected immediately prior to next dose.
Specimen Minimum Volume
0.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Clozapine
Therapeutic range: 350-600 ng/mL
Norclozapine
Therapeutic range: Not well established
Clozapine + Norclozapine
Therapeutic range: Not well established
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80159
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Sanford Interface Build Information
| Result Code | Result Code Description |
|---|---|
| 16286 | Norclozapine |
| 16287 | Clozapine |
| 17178 | Clozapine + Norclozapine Total |