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Test ID BLOD0099 Lipoprotein Metabolism Profile


Necessary Information


Patient's age and sex are required.



Specimen Required


Patient Preparation:

1. Fasting-overnight (12-14 hours)

2. Patient must not consume any alcohol for 24 hours before the specimen is drawn.

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 5 mL


Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.

Useful For

Diagnosing dyslipoproteinemia

 

Quantitation of cholesterol and triglycerides in very-low-density lipoprotein (VLDL), LDL, HDL, and chylomicrons

 

Identification of LpX

 

Classifying hyperlipoproteinemias (lipoprotein phenotyping)

 

Evaluating patients with abnormal lipid values (cholesterol, triglyceride, HDL, LDL)

 

Quantifying lipoprotein a (Lp[a]) cholesterol

Profile Information

Test ID Reporting Name Available Separately Always Performed
TCS Cholesterol, Total, CDC, S No Yes
TRIGC Triglycerides, CDC, S No Yes
APLBS Apolipoprotein B, S No Yes
HDLS HDL Cholesterol, CDC, S No Yes
LMPP1 Lipoprotein Metabolism Profile 1 No Yes

Method Name

Ultracentrifugation/Electrophoresis/Automated Enzymatic/Colorimetric Analysis

Reporting Name

Lipoprotein Metabolism Profile

Specimen Type

Serum

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  60 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross reject

Other

NA

Reference Values

Age

2-9 years

10-17 years

>18 years

Total Cholesterol (mg/dL)

**

Acceptable: <170

Borderline high: 170-199

High: ≥200

*

Desirable: < 200

Borderline high: 200 - 239

High: ≥ 240

Triglycerides (mg/dL)

**

Acceptable: <75 

Borderline high: 75-99

High: ≥100

**

Acceptable: <90 

Borderline high: 90-129

High: ≥130

*

Normal: <150

Borderline high: 150-199

High: 200-499

Very high: ≥500

LDL Cholesterol (mg/dL)

**

Acceptable: <110

Borderline high: 110-129

High: ≥130

***

Desirable: <100

Above Desirable: 100-129

Borderline high: 130-159

High: 160-189

Very high: ≥190

LDL Triglycerides (mg/dL)

≤ 50

≤ 50

Apolipoprotein B (mg/dL)

**

Acceptable: <90

Borderline high: 90-109

High: ≥110

Desirable: <90

Above Desirable: 90-99

Borderline high: 100-119

High: 120-139

Very high: ≥140

HDL Cholesterol (mg/dL)

**

Low: <40

Borderline low: 40-45

Acceptable: > 45

***

Males: ≥40

Females: ≥50

 

VLDL Cholesterol (mg/dL)

<30

<30

VLDLTriglycerides (mg/dL)

<90

<120

Beta VLDL Cholesterol (mg/dL)

<15

<15

Beta VLDL

Triglycerides (mg/dL)

<15

<15

Chylomicron Cholesterol

Undetectable

Undetectable

Chylomicron Triglycerides

Undetectable

Undetectable

Lp(a) cholesterol

<3

<3

LpX

Undetectable

Undetectable

 

Reference values have not been established for patients that are <2 years of age.

*National Cholesterol Education Program (NCEP)

**Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents

***National Lipid Association

Day(s) and Time(s) Performed

Monday through Saturday; 4 p.m.

Analytic Time

3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80061-Lipid panel (includes: HDL [CPT Code 83718], total cholesterol [CPT Code 82465], and triglycerides [CPT Code 84478])

82172-Apolipoprotein B

83700-Lp(a) cholesterol electrophoresis